Join Us in the Fight Against Tay-Sachs Disease

Donate now to make a difference and make a cure

The Cure Tay-Sachs Foundation is dedicated to funding the on-going research needed to find treatments and a cure for Tay-Sachs Disease. Once the cure for Tay-Sachs has been found – and we will find it! – we will dedicate our efforts to promoting carrier-testing and Tay-Sachs awareness initiatives.

is when Cure Tay–Sachs Foundation 
was founded


raised from thousands 
of generous donors


grants to world-class researchers/laboratories around the world

What is Tay-Sachs Disease?

Tay-Sachs disease (TSD) is an inherited condition caused by mutations in the Hex-A gene. This mutation leads to extremely low or non-existent levels of the Hex-A enzyme. Consequently, cells, particularly nerve cells in the brain, fail to eliminate fatty waste products, which accumulate and cause cell death. Since the identification of the Hex-A gene in 1985, 75 to 100 different mutations have been linked to TSD. These mutations may result in different forms of the disease: Infantile (most common), Juvenile, or Late Onset. The Infantile and Juvenile forms are untreatable, inevitably leading to fatality, while the Late Onset form, although slower, is progressive as cells gradually fill with waste.

Begin the journey into Tay-Sachs Awareness today.

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Learn more about Tay-Sachs Disease

Our Research

The Cure Tay-Sachs Foundation’s primary objective is to financially support research initiatives that hold potential in developing a treatment, and ultimately, a cure for Tay-Sachs Disease (TSD). Acknowledging that the complexity of these research concepts can often be daunting for the average individual, our mission includes bridging this knowledge gap.

There is hope in your help